Professor (joint with Biology, Molecular Biology, and Cellular Biology)
PhD, Massachusetts Institute of Technology, 1989
NSF Faculty Early Career Development Award
Professor Marko works on the application of statistical mechanics and polymer physics to biophysical problems, and in particular to micromechanical studies of DNA, DNA-protein interactions, and chromosome structure. At present Prof. Marko's research group carries out both experimental and theoretical research.
Representative Publications
- Bai H, Sun M, Ghosh P, Hatfull GF, Grindley ND, Marko JF.
- D. Skoko, J. Yan, R. C. Johnson, and J.F. Marko
Low-Force DNA Condensation and Discontinuous High-Force Decondensation Reveal a Loop-Stabilizing Function of the Protein Fis
Physical Review Letters 95, 208101 (2005)
Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase.
Proc Natl Acad Sci U S A. 108, 7419-24 (2011)
- J. Yan, R. Kawamura, and J. F. Marko
Statistics of Loop Formation along Double Helix DNAs
Physical Review E71, 061905 (2005)
- J. F. Marko and S. Cocco
The Micromechanics of DNA
Physics World 16, No.3, p 37 (2003)
- M. G. Poirier and J. F. Marko
Mitotic Chromosomes are Chromatin Networks Without an Internal Protein Scaffold
Proceedings of the National Academy of Sciences of the USA 99, 15393 (2002)
